Our paper “Targeted stress granule regulation by engineering a non-catalytic O-GlcNAc transferase” is now published in Nature Communications. By engineering a non-catalytic mutant of O-GlcNAc transferase, we achieve targeted regulation of cellular stress granules and uncover a previously underappreciated non-enzymatic role for OGT in cellular stress responses.
Nat Commun | Unlocking a non-catalytic function of OGT for targeted stress-granule control
Our Nature Communications paper reveals a non-catalytic function of OGT that enables targeted regulation of stress granules.
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2026-09-28Conferences
2026-08-05Publications
GCE Symposium Successfully Held in Shenzhen | Yun Ge Serves on the Organizing Committee
The SMART Symposium on the Expanding Genetic Code and Beyond and GCE Workshop concluded successfully in Shenzhen, with Yun Ge serving on the organizing committee.
Protein & Cell | O-GlcNAc clusters regulate transcriptional condensates
In collaboration with Prof. Jun Liu's team, we report that O-GlcNAc clusters within disordered regions of transcriptional regulators control the material properties of …